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water activity excipients powder sample in laboratory setting

Water Activity Excipients: 7 Facts Formulators Get Wrong About Moisture

Water Activity Excipients: 7 Facts Formulators Get Wrong About Moisture Most Certificates of Analysis for water activity excipients still report only one moisture number: LOD, loss on drying. It’s easy to measure and easy to put on a spec sheet. On its own, though, it’s a surprisingly poor predictor of whether an excipient will destabilize […]

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Nutraceutical dosage form defects cover image showing nine product formats

Nutraceutical Dosage Form Defects: 3 Root Causes Explained

Nutraceutical Dosage Form Defects: 3 Root Causes Explained Nutraceutical dosage form defects are almost never bad luck, and they are rarely confined to a single batch. A recent industry-wide technical review covering nine dosage forms — powder drink mixes, hard capsules, soft gels, tablets, gummies, oil drops, stick-pack liquids, glass-bottled liquids, and granulation — found

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Capsule shell defects cover image showing cracked and intact capsules

Capsule Shell Defects: What’s Really Causing Them

Ashwagandha Extract Sourcing Guide: What Supplement Brands Need To Know Capsule shell defects rarely start with the shell itself — they start with the environment the shell sits in, and how that environment interacts with what is inside it. Shell brittleness and cracking, cap and body separation, powder leakage, and shells that soften and stick

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Pharmacopoeia compliance COA cover image showing USP and Ph Eur comparison

Pharmacopoeia Compliance: 5 Costly Gaps Hiding in Your COA

Pharmacopoeia Compliance: 5 Costly Gaps Hiding in Your COA Your COA says compliant. But compliant to which pharmacopoeia, for which target market, and did the test method actually match your finished product’s registration requirements? In nutraceutical ingredient procurement, pharmacopoeia compliance has quietly become the gap that surfaces at the worst possible moment — during a

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Nutraceutical ingredient sourcing from China cost comparison cover image

Nutraceutical Ingredient Sourcing From China: The Hidden Cost Guide

Nutraceutical Ingredient Sourcing From China: The Hidden Cost Guide Nutraceutical ingredient sourcing from China now accounts for more than 60 percent of global output, and for procurement managers and R&D directors at OEM and ODM factories, that shift changes the math on almost every raw material line item. If your current COA reads 99 percent

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curcuminoid COA analysis HPLC testing guide

Curcuminoid COA Analysis: 5 Questions to Ask Before You Approve a Batch

Curcuminoid COA Analysis: 5 Questions to Ask Before You Approve a Batch Every week, procurement teams and formulators approve ingredient purchases based on a single number printed on a Certificate of Analysis — “95% curcuminoids by HPLC.” It looks authoritative. It looks scientific. It can also be incomplete. A proper curcuminoid COA analysis goes beyond

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pharmacopoeial grade ingredient supplier testing standards guide

Pharmacopoeial Grade Ingredient Supplier: 6 Critical Testing Gaps to Avoid

Pharmacopoeial Grade Ingredient Supplier: 6 Critical Testing Gaps to Avoid Most procurement conversations stop at the Certificate of Analysis. Fewer stop at the question that actually matters: which pharmacopoeial standard was that CoA tested against — and does it match your finished product’s target market? USP, Ph. Eur., and BP are not interchangeable labels. They

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China ingredient supplier sourcing guide 2026

China Ingredient Supplier: 7 Critical Reasons You’re Overpaying in 2026

China Ingredient Supplier: 7 Critical Reasons You’re Overpaying in 2026 If your OEM factory or brand is still sourcing functional ingredients exclusively from Western suppliers, you may be paying significantly more than necessary. Working with a China ingredient supplier is no longer just a cost play — it reflects a structural shift in how the

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